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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPN5
All Species:
17.27
Human Site:
Y437
Identified Species:
34.55
UniProt:
O15484
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15484
NP_004046.2
640
73169
Y437
K
V
E
E
N
R
Q
Y
R
M
H
S
L
Q
H
Chimpanzee
Pan troglodytes
XP_001146965
641
74541
L436
E
M
N
R
K
F
R
L
H
H
L
Y
I
Q
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542293
640
73142
Y437
K
V
E
E
N
R
Q
Y
R
M
H
S
L
Q
H
Cat
Felis silvestris
Mouse
Mus musculus
O08688
640
72936
Y437
K
V
E
E
N
R
Q
Y
R
M
H
S
L
Q
H
Rat
Rattus norvegicus
Q8R4C0
640
73046
Y437
K
V
E
E
N
R
Q
Y
R
M
H
S
L
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518356
408
46381
N221
V
S
S
S
I
Y
I
N
S
R
S
V
F
L
R
Chicken
Gallus gallus
Q92177
810
93542
D516
T
K
H
H
L
Q
K
D
F
F
L
Y
N
A
S
Frog
Xenopus laevis
NP_001080808
642
73235
F437
Q
V
E
L
N
R
K
F
R
M
H
T
L
Q
P
Zebra Danio
Brachydanio rerio
XP_001345114
642
73723
Y437
R
V
E
L
N
R
K
Y
R
M
H
S
A
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q11002
828
93944
N494
E
N
R
P
Q
G
L
N
F
F
R
Y
K
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22036
648
73596
Q448
M
K
V
E
N
N
R
Q
Y
R
V
H
T
A
M
Sea Urchin
Strong. purpuratus
XP_792213
642
72430
H435
E
V
E
S
N
R
K
H
R
A
H
T
I
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
N.A.
92
N.A.
92.1
90.6
N.A.
51.4
30.8
73.9
71.6
N.A.
30.7
N.A.
40.1
47.6
Protein Similarity:
100
65.5
N.A.
95.6
N.A.
96
94.8
N.A.
57.3
46.9
86.2
83.8
N.A.
45.2
N.A.
57.2
64.9
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
0
0
60
66.6
N.A.
0
N.A.
13.3
40
P-Site Similarity:
100
33.3
N.A.
100
N.A.
100
100
N.A.
0
13.3
86.6
80
N.A.
6.6
N.A.
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
9
0
0
9
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
25
0
59
42
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
9
0
9
17
17
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
9
0
0
0
9
9
9
59
9
0
0
34
% H
% Ile:
0
0
0
0
9
0
9
0
0
0
0
0
17
0
0
% I
% Lys:
34
17
0
0
9
0
34
0
0
0
0
0
9
9
0
% K
% Leu:
0
0
0
17
9
0
9
9
0
0
17
0
42
9
0
% L
% Met:
9
9
0
0
0
0
0
0
0
50
0
0
0
0
9
% M
% Asn:
0
9
9
0
67
9
0
17
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
17
% P
% Gln:
9
0
0
0
9
9
34
9
0
0
0
0
0
59
9
% Q
% Arg:
9
0
9
9
0
59
17
0
59
17
9
0
0
0
9
% R
% Ser:
0
9
9
17
0
0
0
0
9
0
9
42
0
9
17
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
0
17
9
0
0
% T
% Val:
9
59
9
0
0
0
0
0
0
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
42
9
0
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _